The Patriarch (also known as the Patty by various community players) is the boss in Killing Floor. The Patriarch was a mad scientist CEO that founded Horzine named Kevin Clamely. He developed the Specimens for a super soldier program for Great Britain.

The Patriarch is the boss in Killing Floor, and will appear at the end of the game. See Rounds page for more information. The Patriarch wears glasses, has tentacles sticking out of his body, and in the middle of his chest, is a tentacle grabber.

His attacks consist of:

• Melee: Using his right hand to hit. He's hands are huge claws.
• Bullets: On his left arm, he has a body-mounted Chaingun, which is easy to doge by hiding behind a wall, or a table.
• Rockets: He will switch between the Chaingun and Rocket Launcher after every ranged attack he makes. He then says a line, and fires a rocket. The rocket can wipe out an entire team if they are too close to each other, so don't stand in groups.

Despite the Patriarch having a lot of health (depending on the Difficulty chosen), he is hard to stun. Using explosives, such as the M32, is the best way to deal with him. If playing on Suicidal, or higher, it is NOT recommended to use close-range weapons, such as the Berserker Perk

The Patriarch spawns with three stimpaks (two on easy), and will heal himself when stunned; once at 50% health, once at 25% health, and once at 10% health. When he is taking the third dose, make a run for it and fire all your Grenades at him, or other explosives. He is weak, and if using the Commando perk, it is easy to follow him to his healing spot. Note that he will not regain full life at any time.